Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster

Deletions, commonly referred to as deficiencies by Drosophila geneticists, are valuable tools for mapping genes and for genetic pathway discovery via dose-dependent suppressor and enhancer screens. More recently, it has become clear that deviations from normal gene dosage are associated with multipl...

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Udgivet i:PLoS Genet
Main Authors: Lee, Hangnoh, Cho, Dong-Yeon, Whitworth, Cale, Eisman, Robert, Phelps, Melissa, Roote, John, Kaufman, Thomas, Cook, Kevin, Russell, Steven, Przytycka, Teresa, Oliver, Brian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012587/
https://ncbi.nlm.nih.gov/pubmed/27599372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006295
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