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Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila

Gene regulatory networks (GRNs) describe regulatory relationships between transcription factors (TFs) and their target genes. Computational methods to infer GRNs typically combine evidence across different conditions to infer context-agnostic networks. We develop a method, Network Reprogramming usin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Yijie, Cho, Dong-Yeon, Lee, Hangnoh, Fear, Justin, Oliver, Brian, Przytycka, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170494/
https://ncbi.nlm.nih.gov/pubmed/30283019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06382-z
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