Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies

Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the tight junction protein claudin-2 by cytokines is hypothesized to contribute to the dysregulation of the epithelial barrier. New therapeutic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Randall, Kevin, Henderson, Neil, Reens, Jaimini, Eckersley, Sonia, Nyström, Ann-Christin, South, Marie C., Balendran, Clare A., Böttcher, Gerhard, Hughes, Glen, Price, Sally A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012586/
https://ncbi.nlm.nih.gov/pubmed/27598247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162076
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