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Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory

Major depressive disorder is often associated with deficits in social and cognitive functioning. Mice transgenic for acid sphingomyelinase (t-ASM) were previously shown to have a depressive-like phenotype, which could be normalized by antidepressant treatment. Here, we investigated whether t-ASM mic...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Zoicas, Iulia, Reichel, Martin, Gulbins, Erich, Kornhuber, Johannes
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012580/
https://ncbi.nlm.nih.gov/pubmed/27598773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162498
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