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Single Molecule Studies of the Diffusion of Band 3 in Sickle Cell Erythrocytes

Sickle cell disease (SCD) is caused by an inherited mutation in hemoglobin that leads to sickle hemoglobin (HbS) polymerization and premature HbS denaturation. Previous publications have shown that HbS denaturation is followed by binding of denatured HbS (a.k.a. hemichromes) to band 3, the consequen...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Spector, Jeff, Kodippili, Gayani C., Ritchie, Ken, Low, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012561/
https://ncbi.nlm.nih.gov/pubmed/27598991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162514
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