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Single Molecule Studies of the Diffusion of Band 3 in Sickle Cell Erythrocytes

Sickle cell disease (SCD) is caused by an inherited mutation in hemoglobin that leads to sickle hemoglobin (HbS) polymerization and premature HbS denaturation. Previous publications have shown that HbS denaturation is followed by binding of denatured HbS (a.k.a. hemichromes) to band 3, the consequen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Spector, Jeff, Kodippili, Gayani C., Ritchie, Ken, Low, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012561/
https://ncbi.nlm.nih.gov/pubmed/27598991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162514
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