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Hyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis

Hyaluronan is the predominant glycosaminoglycan component of the extracellular matrix with an emerging role in hematopoiesis. Modulation of hyaluronan polymer size is responsible for its control over cellular functions, and the balance of hyaluronan synthesis and degradation determines its molecular...

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Bibliografiska uppgifter
I publikationen:Am J Pathol
Huvudupphovsmän: Petrey, Aaron C., Obery, Dana R., Kessler, Sean P., Flamion, Bruno, de la Motte, Carol A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012466/
https://ncbi.nlm.nih.gov/pubmed/27398974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.05.004
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