Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis

Mechanical forces trigger biological responses in bone cells that ultimately control osteoblastogenesis and bone program. Although several mechanosensors have been postulated, the precise mechanotransduction pathway remains obscure as the initial mechanosensing event has not yet been identified. Stu...

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Библиографические подробности
Опубликовано в: :Cell Mol Life Sci
Главные авторы: Dalagiorgou, Georgia, Piperi, Christina, Georgopoulou, Urania, Adamopoulos, Christos, Basdra, Efthimia K., Papavassiliou, Athanasios G.
Формат: Artigo
Язык:Inglês
Опубликовано: SP Birkhäuser Verlag Basel 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012114/
https://ncbi.nlm.nih.gov/pubmed/23014991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1164-5
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