Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis

Mechanical forces trigger biological responses in bone cells that ultimately control osteoblastogenesis and bone program. Although several mechanosensors have been postulated, the precise mechanotransduction pathway remains obscure as the initial mechanosensing event has not yet been identified. Stu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Life Sci
Prif Awduron: Dalagiorgou, Georgia, Piperi, Christina, Georgopoulou, Urania, Adamopoulos, Christos, Basdra, Efthimia K., Papavassiliou, Athanasios G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SP Birkhäuser Verlag Basel 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012114/
https://ncbi.nlm.nih.gov/pubmed/23014991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1164-5
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