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Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis

Mechanical forces trigger biological responses in bone cells that ultimately control osteoblastogenesis and bone program. Although several mechanosensors have been postulated, the precise mechanotransduction pathway remains obscure as the initial mechanosensing event has not yet been identified. Stu...

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Bibliografische gegevens
Gepubliceerd in:Cell Mol Life Sci
Hoofdauteurs: Dalagiorgou, Georgia, Piperi, Christina, Georgopoulou, Urania, Adamopoulos, Christos, Basdra, Efthimia K., Papavassiliou, Athanasios G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SP Birkhäuser Verlag Basel 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012114/
https://ncbi.nlm.nih.gov/pubmed/23014991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1164-5
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