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Modification of platinum sensitivity by KEAP1/NRF2 signals in non-small cell lung cancer
BACKGROUND: The objective of this study was to evaluate the effect of platinum-based drugs on nuclear-factor erythroid2 like 2 (NRF2) signaling in non-small cell lung cancer cell lines with or without Kelch-like ECH-associated protein 1 (KEAP1) mutations and to determine the role of NRF2 and KEAP1 o...
Gardado en:
| Publicado en: | J Hematol Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012055/ https://ncbi.nlm.nih.gov/pubmed/27601007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0311-0 |
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