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CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma

BACKGROUND: The acquisition of inappropriate migratory feature is crucial for tumor metastasis. Rho-family GTPases including RhoA are molecular switches that play critical roles in regulating cell movement. We investigated the molecular mechanism underlying CD147 induced RhoA deactivation in hepatoc...

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Bibliografiska uppgifter
I publikationen:Cancer Cell Int
Huvudupphovsmän: Chen, Ruo, Wang, Shi-Jie, Zhang, Yang, Hou, Rong, Jiang, Jian-Li, Cui, Hong-Yong
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012051/
https://ncbi.nlm.nih.gov/pubmed/27601938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0344-z
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