Accuracy of preimplantation genetic screening (PGS) is compromised by degree of mosaicism of human embryos

BACKGROUND: To preclude transfer of aneuploid embryos, current preimplantation genetic screening (PGS) usually involves one trophectoderm biopsy at blastocyst stage, assumed to represent embryo ploidy. Whether one such biopsy can correctly assess embryo ploidy has recently, however, been questioned....

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Gleicher, Norbert, Vidali, Andrea, Braverman, Jeffrey, Kushnir, Vitaly A., Barad, David H., Hudson, Cynthia, Wu, Yang-Guan, Wang, Qi, Zhang, Lin, Albertini, David F.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011996/
https://ncbi.nlm.nih.gov/pubmed/27595768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-016-0193-6
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