Accuracy of preimplantation genetic screening (PGS) is compromised by degree of mosaicism of human embryos

BACKGROUND: To preclude transfer of aneuploid embryos, current preimplantation genetic screening (PGS) usually involves one trophectoderm biopsy at blastocyst stage, assumed to represent embryo ploidy. Whether one such biopsy can correctly assess embryo ploidy has recently, however, been questioned....

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書目詳細資料
發表在:Reprod Biol Endocrinol
Main Authors: Gleicher, Norbert, Vidali, Andrea, Braverman, Jeffrey, Kushnir, Vitaly A., Barad, David H., Hudson, Cynthia, Wu, Yang-Guan, Wang, Qi, Zhang, Lin, Albertini, David F.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011996/
https://ncbi.nlm.nih.gov/pubmed/27595768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-016-0193-6
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