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Mice with a heterozygous Lrp6 deletion have impaired fracture healing

Bone fracture non-unions, the failure of a fracture to heal, occur in 10%–20% of fractures and are a costly and debilitating clinical problem. The Wnt/β-catenin pathway is critical in bone development and fracture healing. Polymorphisms of linking low-density lipoprotein receptor-related protein 6 (...

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Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Burgers, Travis A, Vivanco, Juan F, Zahatnansky, Juraj, Moren, Andrew J Vander, Mason, James J, Williams, Bart O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011612/
https://ncbi.nlm.nih.gov/pubmed/27635281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2016.25
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