A SCN10A SNP biases human pain sensitivity

BACKGROUND: Nav1.8 sodium channels, encoded by SCN10A, are preferentially expressed in nociceptive neurons and play an important role in human pain. Although rare gain-of-function variants in SCN10A have been identified in individuals with painful peripheral neuropathies, whether more common variant...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Duan, Guangyou, Han, Chongyang, Wang, Qingli, Guo, Shanna, Zhang, Yuhao, Ying, Ying, Huang, Penghao, Zhang, Li, Macala, Lawrence, Shah, Palak, Zhang, Mi, Li, Ningbo, Dib-Hajj, Sulayman D, Waxman, Stephen G, Zhang, Xianwei
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011395/
https://ncbi.nlm.nih.gov/pubmed/27590072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916666083
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