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A variant in the SCN10A enhancer may affect human mechanical pain sensitivity
Expression of Nav1.8, encoded by SCN10A, can affect pain transmission and thus mediate the human pain phenotype. In the current study, we assessed whether the variant rs6801957, located in the SCN10A enhancer region, may have the potential to affect human pain. Through dual-luciferase reporter assay...
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| Publicado no: | Mol Pain |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5858611/ https://ncbi.nlm.nih.gov/pubmed/29448912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806918763275 |
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