A 90-Day Oral Toxicological Evaluation of the Methylurate Purine Alkaloid Theacrine

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on the methylurate purine alkaloid theacrine, which is found naturally in certain plants. Four groups of Hsd.Brl.Han Wistar rats (ten/sex/group) were administered theacrine by gavage doses of 0 (v...

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Vydáno v:J Toxicol
Hlavní autoři: Clewell, Amy, Hirka, Gábor, Glávits, Róbert, Palmer, Philip A., Endres, John R., Murbach, Timothy S., Marx, Tennille, Pasics Szakonyiné, Ilona
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011229/
https://ncbi.nlm.nih.gov/pubmed/27635133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6206859
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