A 90-Day Oral Toxicological Evaluation of the Methylurate Purine Alkaloid Theacrine

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on the methylurate purine alkaloid theacrine, which is found naturally in certain plants. Four groups of Hsd.Brl.Han Wistar rats (ten/sex/group) were administered theacrine by gavage doses of 0 (v...

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Detalhes bibliográficos
Publicado no:J Toxicol
Main Authors: Clewell, Amy, Hirka, Gábor, Glávits, Róbert, Palmer, Philip A., Endres, John R., Murbach, Timothy S., Marx, Tennille, Pasics Szakonyiné, Ilona
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011229/
https://ncbi.nlm.nih.gov/pubmed/27635133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6206859
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