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Intracellular Signaling Pathway Regulation of Myelination and Remyelination in the CNS

The restoration of myelin sheaths on demyelinated axons remains a major obstacle in the treatment of multiple sclerosis (MS). Currently approved therapies work by modulating the immune system to reduce the number and rate of lesion formation but are only partially effective since they are not able t...

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Bibliographic Details
Published in:Exp Neurol
Main Authors: Gaesser, Jenna M., Fyffe-Maricich, Sharyl L.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010983/
https://ncbi.nlm.nih.gov/pubmed/26957369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.03.008
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