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Alterative Expression and Localization of Profilin 1/VASP(pS157) and Cofilin 1/VASP(pS239) Regulates Metastatic Growth and is Modified by DHA Supplementation

Profilin 1, cofilin 1, and vasodialator stimulated phosphoprotein (VASP) are actin binding proteins (ABP) which regulate actin remodelling and facilitate cancer cell metastases. MiR~17–92 is highly expressed in metastatic tumors and profilin1 and cofilin1 are predicted targets. Docosahexaenoic acid...

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Publicado en:Mol Cancer Ther
Main Authors: Ali, Mehboob, Heyob, Kathryn, Jacob, Naduparambil K., Rogers, Lynette K.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010962/
https://ncbi.nlm.nih.gov/pubmed/27496138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0092
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