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Alterative Expression and Localization of Profilin 1/VASP(pS157) and Cofilin 1/VASP(pS239) Regulates Metastatic Growth and is Modified by DHA Supplementation

Profilin 1, cofilin 1, and vasodialator stimulated phosphoprotein (VASP) are actin binding proteins (ABP) which regulate actin remodelling and facilitate cancer cell metastases. MiR~17–92 is highly expressed in metastatic tumors and profilin1 and cofilin1 are predicted targets. Docosahexaenoic acid...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Ali, Mehboob, Heyob, Kathryn, Jacob, Naduparambil K., Rogers, Lynette K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010962/
https://ncbi.nlm.nih.gov/pubmed/27496138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0092
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