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Alterative Expression and Localization of Profilin 1/VASP(pS157) and Cofilin 1/VASP(pS239) Regulates Metastatic Growth and is Modified by DHA Supplementation

Profilin 1, cofilin 1, and vasodialator stimulated phosphoprotein (VASP) are actin binding proteins (ABP) which regulate actin remodelling and facilitate cancer cell metastases. MiR~17–92 is highly expressed in metastatic tumors and profilin1 and cofilin1 are predicted targets. Docosahexaenoic acid...

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Bibliographic Details
Published in:Mol Cancer Ther
Main Authors: Ali, Mehboob, Heyob, Kathryn, Jacob, Naduparambil K., Rogers, Lynette K.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010962/
https://ncbi.nlm.nih.gov/pubmed/27496138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0092
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