Blood-borne LPS is rapidly eliminated by liver sinusoidal endothelial cells via HDL

During Gram-negative bacterial infections, excessive lipopolysaccharide (LPS) induces inflammation and sepsis via action on immune cells. However, the bulk of LPS can be cleared from circulation by the liver. Liver clearance is thought to be a slow process mediated exclusively by phagocytic resident...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yao, Zhili, Mates, Jessica M., Cheplowitz, Alana M., Hammer, Lindsay P., Maiseyeu, Andrei, Phillips, Gary S., Wewers, Mark D., Rajaram, Murugesan V.S., Robinson, John M., Anderson, Clark L., Ganesan, Latha P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010928/
https://ncbi.nlm.nih.gov/pubmed/27534554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600702
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