The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide

BACKGROUND: The toxicity of amyloid-β (Aβ) peptide present in the brain of Alzheimer’s disease (AD) patients is thought to be mediated via the increased secretion of pro-inflammatory mediators, which can lead to neuronal dysfunction and cell death. In addition, we have previously shown that inflamma...

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Bibliografiska uppgifter
I publikationen:J Neuroinflammation
Huvudupphovsmän: Ries, Miriam, Loiola, Rodrigo, Shah, Urvi N., Gentleman, Steve M., Solito, Egle, Sastre, Magdalena
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010757/
https://ncbi.nlm.nih.gov/pubmed/27590054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0692-6
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