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Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-β and tau pathology

Alzheimer’s disease, characterized by brain deposits of amyloid-β plaques and neurofibrillary tangles, is also linked to neurovascular dysfunction and blood–brain barrier breakdown, affecting the passage of substances into and out of the brain. We hypothesized that treatment of neurovascular alterat...

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Détails bibliographiques
Publié dans:Brain
Auteurs principaux: Ries, Miriam, Watts, Helena, Mota, Bibiana C, Lopez, Maria Yanez, Donat, Cornelius K, Baxan, Nicoleta, Pickering, James A, Chau, Tsz Wing, Semmler, Annika, Gurung, Brinda, Aleksynas, Robertas, Abelleira-Hervas, Laura, Iqbal, Soha Jamshed, Romero-Molina, Carmen, Hernandez-Mir, Gerard, d’Amati, Antonio, Reutelingsperger, Chris, Goldfinger, Marc H, Gentleman, Steve M, Van Leuven, Fred, Solito, Egle, Sastre, Magdalena
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262982/
https://ncbi.nlm.nih.gov/pubmed/34148071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab050
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