Macrophage migration inhibitory factor (MIF) supports homing of osteoclast precursors to peripheral osteolytic lesions

By binding to its chemokine receptor CXCR4 on osteoclast precursor cells (OCPs), it is well known that SDF-1 promotes the chemotactic recruitment of circulating OCPs to the homeostatic bone remodeling site. However, the engagement of circulating OCPs in pathogenic bone resorption remains to be eluci...

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Pubblicato in:J Bone Miner Res
Autori principali: Movila, Alexandru, Ishii, Takenobu, Albassam, Abdullah, Wisitrasameewong, Wichaya, Howait, Mohammed, Yamaguchi, Tsuguno, Ruiz-Torruella, Montserrat, Bahammam, Laila, Nishimura, Kazuaki, Van Dyke, Thomas, Kawai, Toshihisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010512/
https://ncbi.nlm.nih.gov/pubmed/27082509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2854
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