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Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer

Combination therapy has become a major strategy in cancer treatment. We used anisamide-targeted lipid–calcium–phosphate (LCP) nanoparticles to efficiently deliver HIF1α siRNA to the cytoplasm of sigma receptor-expressing SCC4 and SAS cells that were also subjected to photodynamic therapy (PDT). HIF1...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Chen, Wei-Hua, Lecaros, Rumwald Leo G., Tseng, Yu-Cheng, Huang, Leaf, Hsu, Yih-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010227/
https://ncbi.nlm.nih.gov/pubmed/25596376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.12.052
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