GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Pyroptosis is a lytic type of cell death that is initiated by inflammatory caspases. These caspases are activated within multi‐protein inflammasome complexes that assemble in response to pathogens and endogenous danger signals. Pyroptotic cell death has been proposed to proceed via the formation of...

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Veröffentlicht in:EMBO J
Hauptverfasser: Sborgi, Lorenzo, Rühl, Sebastian, Mulvihill, Estefania, Pipercevic, Joka, Heilig, Rosalie, Stahlberg, Henning, Farady, Christopher J, Müller, Daniel J, Broz, Petr, Hiller, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010048/
https://ncbi.nlm.nih.gov/pubmed/27418190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694696
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