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Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis

Resilience of Mycobacterium tuberculosis (MTB) emerges from its ability to effectively counteract immunological, environmental, and antitubercular challenges. Here, we demonstrate that MTB can tolerate drug treatment by adopting a tolerant state that can be deciphered through systems analysis of its...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Peterson, Eliza J.R., Ma, Shuyi, Sherman, David R., Baliga, Nitin S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010021/
https://ncbi.nlm.nih.gov/pubmed/27573104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.78
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