Modafinil improves methamphetamine-induced object recognition deficits and restores prefrontal cortex ERK signaling in mice

Chronic use of methamphetamine (METH) leads to long-lasting cognitive dysfunction in humans and in animal models. Modafinil is a wake-promoting compound approved for the treatment of sleeping disorders. It is also prescribed off label to treat METH dependence. In the present study, we investigated w...

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Udgivet i:Neuropharmacology
Main Authors: Gonzalez, Betina, Raineri, Mariana, Cadet, Jean Lud, García-Rill, Edgar, Urbano, Francisco J., Bisagno, Veronica
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010009/
https://ncbi.nlm.nih.gov/pubmed/24530829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.02.002
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