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An augmented CO(2) chemoreflex and overactive orexin system are linked with hypertension in young and adult spontaneously hypertensive rats

KEY POINTS: Activation of central chemoreceptors by CO(2) increases sympathetic nerve activity (SNA), arterial blood pressure (ABP) and breathing. These effects are exaggerated in spontaneously hypertensive rats (SHRs), resulting in an augmented CO(2) chemoreflex that affects both breathing and ABP....

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Vydáno v:J Physiol
Hlavní autoři: Li, Aihua, Roy, Sarah H., Nattie, Eugene E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009771/
https://ncbi.nlm.nih.gov/pubmed/27061304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272199
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