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Antagonism of orexin receptors significantly lowers blood pressure in spontaneously hypertensive rats
In normal rats, central administration of orexin or exposure to certain forms of stress can induce significant increases in blood pressure and sympathetic nerve activity, which can be blocked by orexin receptor antagonists. The resting blood pressure is, however, unaffected by such antagonists, but...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Science Inc
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779114/ https://ncbi.nlm.nih.gov/pubmed/23671161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.256271 |
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