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DNA compaction by the bacteriophage protein Cox studied on the single DNA molecule level using nanofluidic channels

The Cox protein from bacteriophage P2 forms oligomeric filaments and it has been proposed that DNA can be wound up around these filaments, similar to how histones condense DNA. We here use fluorescence microscopy to study single DNA–Cox complexes in nanofluidic channels and compare how the Cox homol...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Frykholm, Karolin, Berntsson, Ronnie Per-Arne, Claesson, Magnus, de Battice, Laura, Odegrip, Richard, Stenmark, Pål, Westerlund, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009727/
https://ncbi.nlm.nih.gov/pubmed/27131370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw352
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