Systemic inflammation disrupts oligodendrocyte gap junctions and induces ER stress in a model of CNS manifestations of X-linked Charcot-Marie-Tooth disease

X-linked Charcot-Marie-Tooth disease (CMT1X) is a common form of inherited neuropathy resulting from different mutations affecting the gap junction (GJ) protein connexin32 (Cx32). A subset of CMT1X patients may additionally present with acute fulminant CNS dysfunction, typically triggered by conditi...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol Commun
Main Authors: Olympiou, Margarita, Sargiannidou, Irene, Markoullis, Kyriaki, Karaiskos, Christos, Kagiava, Alexia, Kyriakoudi, Styliana, Abrams, Charles K., Kleopa, Kleopas A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009701/
https://ncbi.nlm.nih.gov/pubmed/27585976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0369-5
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