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A rapid method for quantifying free and bound acetate based on alkylation and GC-MS analysis

BACKGROUND: Acetyl-CoA is a key metabolic intermediate with roles in the production of energy and biomass, as well as in metabolic regulation. It was recently found that acetate is crucial for maintaining acetyl-CoA production in hypoxic cancer cells. However, the availability of free acetate in the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Metab
Main Authors: Tumanov, Sergey, Bulusu, Vinay, Gottlieb, Eyal, Kamphorst, Jurre J.
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009658/
https://ncbi.nlm.nih.gov/pubmed/27594997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-016-0157-5
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