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Dietary Manganese Modulates PCB126 Toxicity, Metal Status, and MnSOD in the Rat

PCB126 (3,3′,4,4′,5-pentachlorobiphenyl) is a potent aryl hydrocarbon receptor agonist and induces oxidative stress. Because liver manganese (Mn) levels decrease in response to PCB126, a Mn dietary study was designed to investigate the role of Mn in PCB126 toxicity. Male Sprague Dawley rats received...

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Dettagli Bibliografici
Pubblicato in:Toxicol Sci
Autori principali: Wang, Bingxuan, Klaren, William D., Wels, Brian R., Simmons, Donald L., Olivier, Alicia K., Wang, Kai, Robertson, Larry W., Ludewig, Gabriele
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009614/
https://ncbi.nlm.nih.gov/pubmed/26660635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv312
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