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Dietary Manganese Modulates PCB126 Toxicity, Metal Status, and MnSOD in the Rat

PCB126 (3,3′,4,4′,5-pentachlorobiphenyl) is a potent aryl hydrocarbon receptor agonist and induces oxidative stress. Because liver manganese (Mn) levels decrease in response to PCB126, a Mn dietary study was designed to investigate the role of Mn in PCB126 toxicity. Male Sprague Dawley rats received...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Wang, Bingxuan, Klaren, William D., Wels, Brian R., Simmons, Donald L., Olivier, Alicia K., Wang, Kai, Robertson, Larry W., Ludewig, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009614/
https://ncbi.nlm.nih.gov/pubmed/26660635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv312
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