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Discovery of Transcriptional Targets Regulated by Nuclear Receptors Using a Probabilistic Graphical Model
Nuclear receptors (NRs) are ligand-activated transcriptional regulators that play vital roles in key biological processes such as growth, differentiation, metabolism, reproduction, and morphogenesis. Disruption of NRs can result in adverse health effects such as NR-mediated endocrine disruption. A c...
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| Publicado no: | Toxicol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009613/ https://ncbi.nlm.nih.gov/pubmed/26643261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv261 |
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