Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis

Objectives. Neutrophil elastase (NE), a granule-associated enzyme, participates in connective tissue breakdown and promotes cytokine release and specific receptor activation during various inflammatory diseases like RA. NE is increased in the SF and cartilage of RA patients and represents a target f...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: Di Cesare Mannelli, Lorenzo, Micheli, Laura, Cinci, Lorenzo, Maresca, Mario, Vergelli, Claudia, Pacini, Alessandra, Quinn, Mark T., Paola Giovannoni, Maria, Ghelardini, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Clinical Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009473/
https://ncbi.nlm.nih.gov/pubmed/27032424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kew055
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