Preferential Tim-3 expression on Treg and CD8(+) T cells, supported by tumor-associated macrophages, is associated with worse prognosis in gastric cancer

While infection with H. pylori is a strong risk factor for gastric cancer, most H. pylori-colonized individuals, even those with the high-risk CagA(+)VacA(+) strain, remain asymptomatic over their lifetime. We hypothesized that the discordant outcomes were due to differences in the host immune respo...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Shen, Pinying, Yue, Rongxi, Tang, Jiahong, Si, Haige, Shen, Liqun, Guo, Changsheng, Zhang, Lixin, Han, Huaizhong, Song, Haihan K, Zhao, Pengfei, Wang, Ning, Song, Zongchang, Guo, Chunliang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009394/
https://ncbi.nlm.nih.gov/pubmed/27648132
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