Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells

Osteolineage cells represent one of the critical bone marrow niche components that support maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies demonstrate that extracellular vesicles (EVs) regulate stem cell development via horizontal transfer of bioactive cargo, including...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morhayim, Jess, van de Peppel, Jeroen, Braakman, Eric, Rombouts, Elwin W. J. C., ter Borg, Mariette N. D., Dudakovic, Amel, Chiba, Hideki, van der Eerden, Bram C. J., Raaijmakers, Marc H., van Wijnen, Andre J., Cornelissen, Jan J., van Leeuwen, Johannes P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009378/
https://ncbi.nlm.nih.gov/pubmed/27585950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32034
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