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Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport

Parathyroid hormone (PTH) and FGF23 are the primary hormones regulating acute phosphate homeostasis. Human renal proximal tubule cells (RPTECs) were used to characterize the mechanism and signaling pathways of PTH and FGF23 on phosphate transport and the role of the PDZ protein NHERF1 in mediating P...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sneddon, W. Bruce, Ruiz, Giovanni W., Gallo, Luciana I., Xiao, Kunhong, Zhang, Qiangmin, Rbaibi, Youssef, Weisz, Ora A., Apodaca, Gerard L., Friedman, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009241/
https://ncbi.nlm.nih.gov/pubmed/27432882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744052
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