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Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression

The variegated expression of murine Ly49 loci has been associated with the probabilistic behavior of an upstream promoter active in immature cells, the Pro1 element. However, recent data suggests that Pro1 may be active in mature NK cells and function as an enhancer element. To directly assess if Pr...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: McCullen, Matthew V., Li, Hongchuan, Cam, Maggie, Sen, Shurjo K., McVicar, Daniel W., Anderson, Stephen K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008998/
https://ncbi.nlm.nih.gov/pubmed/27467282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2016.31
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