Loss of Nlrp3 Does Not Protect Mice from Western Diet-Induced Adipose Tissue Inflammation and Glucose Intolerance

We tested the hypothesis that loss of Nlrp3 would protect mice from Western diet-induced adipose tissue (AT) inflammation and associated glucose intolerance and cardiovascular complications. Five-week old C57BL6J wild-type (WT) and Nlrp3 knockout (Nlrp3(-/-)) mice were randomized to either a control...

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Udgivet i:PLoS One
Main Authors: Ringling, Rebecca E., Gastecki, Michelle L., Woodford, Makenzie L., Lum-Naihe, Kelly J., Grant, Ryan W., Pulakat, Lakshmi, Vieira-Potter, Victoria J., Padilla, Jaume
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008778/
https://ncbi.nlm.nih.gov/pubmed/27583382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161939
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