Mogrol Derived from Siraitia grosvenorii Mogrosides Suppresses 3T3-L1 Adipocyte Differentiation by Reducing cAMP-Response Element-Binding Protein Phosphorylation and Increasing AMP-Activated Protein Kinase Phosphorylation

This study investigated the effects of mogrol, an aglycone of mogrosides from Siraitia grosvenorii, on adipogenesis in 3T3-L1 preadipocytes. Mogrol, but not mogrosides, suppressed triglyceride accumulation by affecting early (days 0–2) and late (days 4–8), but not middle (days 2–4), differentiation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Harada, Naoki, Ishihara, Mikako, Horiuchi, Hiroko, Ito, Yuta, Tabata, Hiromitsu, Suzuki, Yasushi A., Nakano, Yoshihisa, Yamaji, Ryoichi, Inui, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008739/
https://ncbi.nlm.nih.gov/pubmed/27583359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162252
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