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Peptidyl arginine deiminase-4-deficient mice are protected against kidney and liver injury after renal ischemia and reperfusion

We previously demonstrated that renal peptidyl arginine deiminase-4 (PAD4) is induced after renal ischemia and reperfusion (I/R) injury and exacerbates acute kidney injury (AKI) by increasing the renal tubular inflammatory response. Here, we tested whether genetic ablation of PAD4 attenuates renal i...

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Bibliografiset tiedot
Julkaisussa:Am J Physiol Renal Physiol
Päätekijät: Rabadi, May, Kim, Mihwa, D'Agati, Vivette, Lee, H. Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008675/
https://ncbi.nlm.nih.gov/pubmed/27335376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00254.2016
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