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Phosphatidylserine and Phosphatidylethanolamine Bind to Protein Z Cooperatively and with Equal Affinity

Protein Z (PZ) is an anticoagulant that binds with high affinity to Protein Z-dependent protease inhibitor (ZPI) and accelerates the rate of ZPI-mediated inhibition of factor Xa (fXa) by more than 1000-fold in the presence of Ca(2+) and phospholipids. PZ promotion of the ZPI-fXa interaction results...

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Vydáno v:PLoS One
Hlavní autoři: Sengupta, Tanusree, Manoj, Narayanan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008636/
https://ncbi.nlm.nih.gov/pubmed/27584039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161896
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