Genetic variation associated with longer telomere length increases risk of chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. Shorter mean telomere length in leukemic cells has been associated with more aggressive disease. Germline polymorphisms in telomere maintenance genes impact telomere length and may contribute to CLL susc...

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Gepubliceerd in:Cancer Epidemiol Biomarkers Prev
Hoofdauteurs: Ojha, Juhi, Codd, Veryan, Nelson, Christopher P., Samani, Nilesh J., Smirnov, Ivan V., Madsen, Nils R., Hansen, Helen M., de Smith, Adam J., Bracci, Paige M., Wiencke, John K., Wrensch, Margaret R., Wiemels, Joseph L., Walsh, Kyle M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008454/
https://ncbi.nlm.nih.gov/pubmed/27197291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-1329
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