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Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers

Aberrant telomere lengthening is an important feature of cancer cells in adults and children. In addition to somatic mutations, germline polymorphisms in telomere maintenance genes impact telomere length. Whether these telomere-associated polymorphisms affect risk of childhood malignancies remains l...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Walsh, Kyle M., Whitehead, Todd P., de Smith, Adam J., Smirnov, Ivan V., Park, Minsun, Endicott, Alyson A., Francis, Stephen S., Codd, Veryan, Samani, Nilesh J., Metayer, Catherine, Wiemels, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876988/
https://ncbi.nlm.nih.gov/pubmed/27207662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw037
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