Genetic variation associated with longer telomere length increases risk of chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. Shorter mean telomere length in leukemic cells has been associated with more aggressive disease. Germline polymorphisms in telomere maintenance genes impact telomere length and may contribute to CLL susc...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Ojha, Juhi, Codd, Veryan, Nelson, Christopher P., Samani, Nilesh J., Smirnov, Ivan V., Madsen, Nils R., Hansen, Helen M., de Smith, Adam J., Bracci, Paige M., Wiencke, John K., Wrensch, Margaret R., Wiemels, Joseph L., Walsh, Kyle M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008454/
https://ncbi.nlm.nih.gov/pubmed/27197291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-1329
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