Genetic variation associated with longer telomere length increases risk of chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. Shorter mean telomere length in leukemic cells has been associated with more aggressive disease. Germline polymorphisms in telomere maintenance genes impact telomere length and may contribute to CLL susc...

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Udgivet i:Cancer Epidemiol Biomarkers Prev
Main Authors: Ojha, Juhi, Codd, Veryan, Nelson, Christopher P., Samani, Nilesh J., Smirnov, Ivan V., Madsen, Nils R., Hansen, Helen M., de Smith, Adam J., Bracci, Paige M., Wiencke, John K., Wrensch, Margaret R., Wiemels, Joseph L., Walsh, Kyle M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008454/
https://ncbi.nlm.nih.gov/pubmed/27197291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-1329
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