Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis

OBJECTIVE: There is increasing evidence supporting the role of platelets in atherosclerotic vascular disease. The G-protein-coupled receptor P2Y(12) is a central mediator of platelet activation and aggregation but has also been linked to platelet-independent vascular disease. Ticagrelor is an oral P...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Preusch, Michael R, Rusnak, Jonas, Staudacher, Kathrin, Mogler, Carolin, Uhlmann, Lorenz, Sievers, Philipp, Bea, Florian, Katus, Hugo A, Blessing, Erwin, Staudacher, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008449/
https://ncbi.nlm.nih.gov/pubmed/27616880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S105718
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