GDF-15 protects from macrophage accumulation in a mousemodel of advanced atherosclerosis

BACKGROUND: The cytokine growth differentiation factor-15 (GDF-15), a member of the TGF beta superfamily, has recently been discovered to play an important role in cardiovascular diseases. It is mostly expressed in macrophages of atherosclerotic lesions, but its impact on advanced atherosclerosis is...

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Detalhes bibliográficos
Main Authors: Preusch, Michael R, Baeuerle, Matthias, Albrecht, Claudia, Blessing, Erwin, Bischof, Marc, Katus, Hugo A, Bea, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701574/
https://ncbi.nlm.nih.gov/pubmed/23800095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-18-19
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